Difference between revisions of "Make your like simplier"

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Based on the results, it was concluded that the PM significantly increased caregivers' oral health knowledge.<br />This study aimed to determine the prevalence of nonsyndromic congenital sensorineural hearing loss at the Hospital Universitario San Ignacio, Bogotá, Colombia, and to describe the risk factors associated with this condition.<br />A prospective, observational cross-sectional study with bivariate analysis was conducted. A three-phase process using the Otoacoustic Emissions test screened all live newborns between June 2013 and June 2014. Negative cases were confirmed by Automated Auditory Brainstem Response test.<br />A total of 962 newborns were screened with Otoacoustic Emissions test bilaterally 401 males (46.36%), 464 females (53.64%). The mean weight was 2 798.10 g (95%CI 2 766.51 - 2 839.76). The mean height was 48.60 cm (95%CI 48.38 - 48.79). The mean age was 16.24 days (95%CI 15.47 - 17.01). The mean maternal age was 27.37 years (95%CI 26.76 - 27.98). There was a family history of hearing loss in 9.48% of the cases (n=90), and a family history of genetic diseases in 100 cases (10.56%). There were 14 cases of TORCH infections (1.45%), 375 admissions to the NICU (39.06%), 160 cases of neonatal jaundice (20.1%), and 79 cases of postpartum infections (8.21%). One live newborn presented with microtia.<br />The prevalence of congenital sensorineural hearing loss was 0.31% in both ears, and 0.11% in one ear. Currently, Colombia lacks a public universal newborn hearing screening program, and its future implementation faces great challenges.<br />The prevalence of congenital sensorineural hearing loss was 0.31% in both ears, and 0.11% in one ear. Currently, Colombia lacks a public universal newborn hearing screening program, and its future implementation faces great challenges.<br />To explore the perception of stakeholders on the implementation policy of the childhood protection subsystem "Chile Crece Contigo" in the Commune of Concepción, Chile.<br />Qualitative study. Semi-structured interviews and a focus group were used as information gathering techniques. A theoretical sampling was carried out based on the representation of decision and power levels with regard to the implementation of Chile Crece Contigo in the Commune of Concepción. The data were analyzed with the ATLAS.ti 6.2 software.<br />The most notable achievements highlighted by interviewees were the high valuation of Chile Crece Contigo, along with the possibility of placing relevant subjects such as first childhood care into the agenda. On the contrary, taking advantage of benefits delivered by the program and the dissemination of the policy were deemed as not achieved. The main facilitator of the implementation was the commitment of the beneficiaries to Chile Crece Contigo, while the most important barrier identified was the contract modality of professionals. Finally, aspects to be improved included infrastructure of facilities, the Chile Crece Contigo network articulation and the funds to secure sustainability of the program over time.<br />The implementation of Chile Crece Contigo in the Commune of Concepción has achieved high recognition in the community, however, it is still necessary to work on the achievement of aspects related to the articulation of the different stakeholders that make up the Chile Crece Contigo network, the diffusion of politics at all levels, and the best use of the benefits delivered to the population.<br />The implementation of Chile Crece Contigo in the Commune of Concepción has achieved high recognition in the community, however, it is still necessary to work on the achievement of aspects related to the articulation of the different stakeholders that make up the Chile Crece Contigo network, the diffusion of politics at all levels, and the best use of the benefits delivered to the population.<br />To establish the correlation between intestinal parasitism in children younger than 6 years old and their dwelling in environmental protected areas without aqueduct service, in the neighborhood El Codito, in Bogotá, Colombia.<br />A cross-sectional study was done with 144 children between the ages of 4 and 70 months. Socio-demographic data were collected by surveying parents, and fecal samples were taken from the children to identify parasites. [https://www.selleckchem.com/products/avitinib-ac0010.html Abivertinib purchase] Descriptive measures were calculated for the variables by population type (parasitized and non-parasitized), establishing significant differences. Using a binary multivariate logistic regression, the correlation between intestinal parasitism and aqueduct was determined, adjusting the other studied variables.<br />The prevalence of intestinal parasitism was 38.9%. The lack of aqueduct service was associated with intestinal parasitism (OR=31.25) after adjusting for other studied variables, which included affiliation to the subsidized health insurance regime compared with the contributory regime (OR= 1.49), home pets (OR= 2.58), mothers with professional jobs compared to mothers with non-professional jobs (OR=0.05), and dwelling in a rented room when compared with own dwelling (OR= 6.62).<br />Children under the age of 6 living in protected areas without water service were more likely to suffer from intestinal parasitism. It is known that preserving protected areas to protect the environment is of great importance, but if the settlement of populations in these territories is not prevented in time, the population living there is subject to adverse conditions which violate human dignity.<br />Children under the age of 6 living in protected areas without water service were more likely to suffer from intestinal parasitism. It is known that preserving protected areas to protect the environment is of great importance, but if the settlement of populations in these territories is not prevented in time, the population living there is subject to adverse conditions which violate human dignity.<br />To establish the prevalence and characteristics of violence against women living with human immunodeficiency virus infection and to explore factors associated with violence in an HIV care program in the city of Bogotá in 2017.<br />Analytical cross-sectional study design that identified characteristics associated with violence against women living with HIV in the city of Bogotá.<br />Of the 223 women surveyed, 33.6% (95%CI 27-40%) experienced intimate partner violence of any type, physical or non-physical, only physical violence 21.9% (95% CI 16-27%), and non-physical violence 31.8% (95% CI 26-38%). link2 Non-physical partner violence was found to be related to being separated or in a consensual union (32.4 and 28.2%, respectively, p=0.000), to a nuclear family composition (42.3% p=0.041), or to 100% economic contribution of the woman in the household (33.8% p=0.001). On the other hand, physical violence is more frequent in separated women (46.9%, p=0.000), in couples with children (89.8%, p=0.042), in single-parent families (49%, p=0.000), in single women (42.9%, p=0.013), and in women who make 100% economic contribution at home (38.8%, p=38.8).<br />The results related to intimate partner violence in these women suggest that screening should be done to detect violence as part of post-HIV counseling, and that violence should be addressed as a routine part of HIV treatment and care to improve the quality of life for women living with HIV.<br />The results related to intimate partner violence in these women suggest that screening should be done to detect violence as part of post-HIV counseling, and that violence should be addressed as a routine part of HIV treatment and care to improve the quality of life for women living with HIV.<br />To determine the prevalence of mental disorders in children treated at a regional psychiatric hospital.<br />Period prevalence study. A secondary database was supplied by the Hospital Psiquiátrico Universitario del Valle (HPUV) of Santiago de Cali. This database came from the systematized clinical history of the year 2014. The population consisted of underage patients who consulted during the period. All the records available in the database were used.<br />Of the total number of children who visited the clinic, 35.7% (755) were females and 64.3% were males (1 361). The main psychiatric diagnosis observed in this population was depressive episode (11.6%), followed by mixed behavioral and emotional disorder (8.5%).<br />The evolution of mental health over time has not changed significantly. link3 The 2015 National Mental Health Survey presents similar results to those found in this study, particularly in the Pacific region, where depression and behavioral disorders are more prevalent.<br />The evolution of mental health over time has not changed significantly. The 2015 National Mental Health Survey presents similar results to those found in this study, particularly in the Pacific region, where depression and behavioral disorders are more prevalent.<br />To identify and analyze the occurrence of adverse events after vaccination against influenza in Brazilian elderly.<br />Descriptive, analytical, retrospective and quantitative research on 98 elderly people identified through post-vaccination adverse event reporting forms provided by the Post-Vaccination Adverse Events Information System of Minas Gerias, Brazil, between 2014 and 2016. Data were double-entered and transferred to the software Ri386 version 3.4.3 3 IBM SPSS Statics version 25. Descriptive statistics, frequency and percentages were used for qualitative variables, and measures of central tendency (mean and median) and dispersion (standard deviation) were used for numerical variables. In order to verify the association between the types of events (non-severe, severe and immunization error) and systemic manifestations with elderly and vaccine characterization variables, Fisher's exact and Chi-square tests were used; the significance level was p &lt;0.05.<br />Of the elderly studied, 75.5% were female, predominantly Caucasian (55.1%), whose age ranged from 60 to 97 years; 84.7% of adverse events were described as non-adverse events, with local manifestations in 64.3% and systemic manifestations in 27.6%.<br />Providing specific information to nurses regarding pre- and post-vaccination care against influenza is highly relevant for establishing adequate care that is harmless to the elderly and that lead to avoidable adverse events.<br />Providing specific information to nurses regarding pre- and post-vaccination care against influenza is highly relevant for establishing adequate care that is harmless to the elderly and that lead to avoidable adverse events.<br />This study seeks to describe the barriers to access to antenatal care in women with severe maternal morbidity, treated at a hospital in the city of Medellin, Colombia in 2017.<br />Qualitative, ethnographic study using the ethnonursing approach proposed by Leininger, and Spradley's ethnographic interview.<br />Women with severe maternal morbidity consider that the health system does not guarantee access to health for them and their unborn children.<br />It is concluded that the health system, to which the women included in the study are entitled, is not available, which conditions non-attendance to prenatal care programs.<br />It is concluded that the health system, to which the women included in the study are entitled, is not available, which conditions non-attendance to prenatal care programs.
n level, and root to trunk level. Motor complications, transient nerve palsy, and bleeding are among the most common complications of the anterior supraclavicular approach. Further controlled studies are needed to fully determine the optimal surgical approach used to obtain the best outcomes and least complications for each type of brachial plexus tumor.Teratomas of anterior mediastinum are rare tumors and are often slow growing, asymptomatic and detected incidentally on chest imaging. We report, a rare case of an anterior mediastinal teratoma occurring in early childhood. A 4-month-old male infant presented to the pediatric unit of our hospital with a 2-week history of a progressive difficulty in breathing and stridor. He had received several courses of oral and intravenous antibiotics for a clinical diagnosis of pneumonia. The baby started to show social smile and hold his head fairly steady. Chest radiography and chest ultrasound revealed a cystic anterior mediastinal mass which was confirmed by a contrasted chest CT. An ultrasound-guided trucut biopsy of the mass was performed and histopathology showed mature cystic teratoma. Surgical removal of the mass was done with excellent post-operative outcome. Occurrence of a mature cystic anterior mediastinal teratoma is uncommon in early infancy. Early and complete surgical resection offers the best possible prognosis.<br />The first aim is to determine the clinical and pathological characteristics and factors affecting survival in patients with pathological complete response (pCR) after neoadjuvant therapy, and the secondary aim is to investigate the effect of adjuvant therapy on survival in these patients.<br />Between 2003 and 2015, there was 372 patients who underwent lung resection after neoadjuvant therapy with a diagnosis of locally advanced lung cancer. Sixty-eight patients who had pCRwere retrospectively analyzed. The odds ratios (OR) were calculated in regards of recurrence.<br />Overall 5-year survival rate was 65.1%. [https://www.selleckchem.com/products/bay-293.html buy BAY-293] Recurrence was the risk factor affecting survival (78.2% vs 19.3%, p = 0.001) while neoadjuvant treatment type (p = 0.766), the reason of neodjuvant treatment (p = 0.581), and the type of operation (p = 0.860) did not affect survival. Postoperative adjuvant treatment had a positive effect on survival (71.1% versus 62.7%), although this difference was not significant (p = 0.561). Local or distant recurrence was detected in 15 patients (22%). In multivariate analysis, the independent risk factors affecting the recurrence were the time from the end of the neoadjuvant therapy to the surgery being less than eight weeks (OR = 6.49, p = 0.03), the type of neoadjuvant treatment (OR = 0.203, p = 0.03). In patients with a squamous cell carcinoma, there was a decreased trend toward in terms of recurrence (p = 0.06).<br />pCR after neoadjuvant therapy positively affects survival. Better survival may be detected in patients receiving adjuvant therapy. Due to unexpected the high recurrence rate, patients should be followed in the postoperative period closely.<br />pCR after neoadjuvant therapy positively affects survival. Better survival may be detected in patients receiving adjuvant therapy. Due to unexpected the high recurrence rate, patients should be followed in the postoperative period closely.<br />The prognosis of patients with esophageal squamous cell carcinoma (ESCC) has been improved by multidisciplinary therapy with chemoradiotherapy and surgery, but it remains poor. Advanced stage, malignant potential, and chemo-resistance contribute to the poor prognosis. Here, we attempted to identify predictive factors of the response to chemotherapy and the prognosis of ESCC patients.<br />We examined 51 ESCC patients who were treated with chemotherapy followed by radical surgery, and 23 patients who were treated with chemotherapy alone. We conducted quantitative reverse transcription-polymerase chain reaction gene expression analysis using RNA extracted from 74 tumor tissue samples collected before chemotherapy and 67 tumor tissue samples collected after chemotherapy, focusing on PIK3CA, AKT-1, mTOR, 4E-BP1, p70S6K, PD-L1, and PD-L2.<br />The proportions of patients with high expressions of AKT-1 and PD-L1 before chemotherapy were significantly higher among the non-responders than among the responders (p = 0.034, p = 0.020, respectively). Multivariate analyses revealed that high PD-L1 expression before chemotherapy was associated with poor response to chemotherapy (odds ratio 2.998; 95% CI 1.043-8.619; p = 0.042) and high p70S6K expression before chemotherapy was a poor prognostic factor (hazard ratio 2.518; 95% CI 1.058-5.988; p = 0.037). In addition, the patients with high expression of PD-L1 and PD-L2 in the tumors after chemotherapy had significantly worse survival than those with low expression of these genes (p = 0.012, p = 0.007, respectively).<br />These results demonstrated that PD-L1 and p70S6K in the primary ESCC tissues were related to a poor response to chemotherapy and poor prognosis, respectively.<br />These results demonstrated that PD-L1 and p70S6K in the primary ESCC tissues were related to a poor response to chemotherapy and poor prognosis, respectively.The developmental course of antisocial behavior is often described in terms of qualitatively distinct trajectories. However, the genetic etiology of various trajectories is not well understood. We examined heterogeneity in the development of delinquent and aggressive behavior in 1532 twin youth using four waves of data collection, spanning ages 9-10 to 16-18. A latent class growth analysis was used to uncover relevant subgroups. For delinquent behavior, three latent classes emerged Non-Delinquent, Low-Level Delinquent, and Persistent Delinquent. Liability for persistent delinquency had a substantial genetic origin (heritability = 67%), whereas genetic influences were negligible for lower-risk subgroups. Three classes of aggressive behavior were identified Non-Aggressive, Moderate, and High. Moderate heritability spanned the entire continuum of risk for aggressive behavior. Thus, there are differences between aggressive behavior and non-aggressive delinquency with respect to heterogeneity of etiology. We conclude that persistent delinquency represents an etiologically distinct class of rule-breaking with strong genetic roots.

Latest revision as of 07:14, 2 November 2024

n level, and root to trunk level. Motor complications, transient nerve palsy, and bleeding are among the most common complications of the anterior supraclavicular approach. Further controlled studies are needed to fully determine the optimal surgical approach used to obtain the best outcomes and least complications for each type of brachial plexus tumor.Teratomas of anterior mediastinum are rare tumors and are often slow growing, asymptomatic and detected incidentally on chest imaging. We report, a rare case of an anterior mediastinal teratoma occurring in early childhood. A 4-month-old male infant presented to the pediatric unit of our hospital with a 2-week history of a progressive difficulty in breathing and stridor. He had received several courses of oral and intravenous antibiotics for a clinical diagnosis of pneumonia. The baby started to show social smile and hold his head fairly steady. Chest radiography and chest ultrasound revealed a cystic anterior mediastinal mass which was confirmed by a contrasted chest CT. An ultrasound-guided trucut biopsy of the mass was performed and histopathology showed mature cystic teratoma. Surgical removal of the mass was done with excellent post-operative outcome. Occurrence of a mature cystic anterior mediastinal teratoma is uncommon in early infancy. Early and complete surgical resection offers the best possible prognosis.
The first aim is to determine the clinical and pathological characteristics and factors affecting survival in patients with pathological complete response (pCR) after neoadjuvant therapy, and the secondary aim is to investigate the effect of adjuvant therapy on survival in these patients.
Between 2003 and 2015, there was 372 patients who underwent lung resection after neoadjuvant therapy with a diagnosis of locally advanced lung cancer. Sixty-eight patients who had pCRwere retrospectively analyzed. The odds ratios (OR) were calculated in regards of recurrence.
Overall 5-year survival rate was 65.1%. buy BAY-293 Recurrence was the risk factor affecting survival (78.2% vs 19.3%, p = 0.001) while neoadjuvant treatment type (p = 0.766), the reason of neodjuvant treatment (p = 0.581), and the type of operation (p = 0.860) did not affect survival. Postoperative adjuvant treatment had a positive effect on survival (71.1% versus 62.7%), although this difference was not significant (p = 0.561). Local or distant recurrence was detected in 15 patients (22%). In multivariate analysis, the independent risk factors affecting the recurrence were the time from the end of the neoadjuvant therapy to the surgery being less than eight weeks (OR = 6.49, p = 0.03), the type of neoadjuvant treatment (OR = 0.203, p = 0.03). In patients with a squamous cell carcinoma, there was a decreased trend toward in terms of recurrence (p = 0.06).
pCR after neoadjuvant therapy positively affects survival. Better survival may be detected in patients receiving adjuvant therapy. Due to unexpected the high recurrence rate, patients should be followed in the postoperative period closely.
pCR after neoadjuvant therapy positively affects survival. Better survival may be detected in patients receiving adjuvant therapy. Due to unexpected the high recurrence rate, patients should be followed in the postoperative period closely.
The prognosis of patients with esophageal squamous cell carcinoma (ESCC) has been improved by multidisciplinary therapy with chemoradiotherapy and surgery, but it remains poor. Advanced stage, malignant potential, and chemo-resistance contribute to the poor prognosis. Here, we attempted to identify predictive factors of the response to chemotherapy and the prognosis of ESCC patients.
We examined 51 ESCC patients who were treated with chemotherapy followed by radical surgery, and 23 patients who were treated with chemotherapy alone. We conducted quantitative reverse transcription-polymerase chain reaction gene expression analysis using RNA extracted from 74 tumor tissue samples collected before chemotherapy and 67 tumor tissue samples collected after chemotherapy, focusing on PIK3CA, AKT-1, mTOR, 4E-BP1, p70S6K, PD-L1, and PD-L2.
The proportions of patients with high expressions of AKT-1 and PD-L1 before chemotherapy were significantly higher among the non-responders than among the responders (p = 0.034, p = 0.020, respectively). Multivariate analyses revealed that high PD-L1 expression before chemotherapy was associated with poor response to chemotherapy (odds ratio 2.998; 95% CI 1.043-8.619; p = 0.042) and high p70S6K expression before chemotherapy was a poor prognostic factor (hazard ratio 2.518; 95% CI 1.058-5.988; p = 0.037). In addition, the patients with high expression of PD-L1 and PD-L2 in the tumors after chemotherapy had significantly worse survival than those with low expression of these genes (p = 0.012, p = 0.007, respectively).
These results demonstrated that PD-L1 and p70S6K in the primary ESCC tissues were related to a poor response to chemotherapy and poor prognosis, respectively.
These results demonstrated that PD-L1 and p70S6K in the primary ESCC tissues were related to a poor response to chemotherapy and poor prognosis, respectively.The developmental course of antisocial behavior is often described in terms of qualitatively distinct trajectories. However, the genetic etiology of various trajectories is not well understood. We examined heterogeneity in the development of delinquent and aggressive behavior in 1532 twin youth using four waves of data collection, spanning ages 9-10 to 16-18. A latent class growth analysis was used to uncover relevant subgroups. For delinquent behavior, three latent classes emerged Non-Delinquent, Low-Level Delinquent, and Persistent Delinquent. Liability for persistent delinquency had a substantial genetic origin (heritability = 67%), whereas genetic influences were negligible for lower-risk subgroups. Three classes of aggressive behavior were identified Non-Aggressive, Moderate, and High. Moderate heritability spanned the entire continuum of risk for aggressive behavior. Thus, there are differences between aggressive behavior and non-aggressive delinquency with respect to heterogeneity of etiology. We conclude that persistent delinquency represents an etiologically distinct class of rule-breaking with strong genetic roots.