Kids accept to as well as apply prosocial but not selfcentered revealing standards

Among the most frequent combinations of comorbidities, the most prevalent comorbidity was chronic heart disease. Other high prevalent comorbidities included mood disorders, arthropathy and arthritis, and esophageal disorders. The ratio of chronic versus acute diseases was approximately 21. Multimorbidity affected almost 90% of patients, with a median of five chronic diseases. Over 10% had ≥ 10 chronic diseases. This identification and quantification of frequent combinations of comorbidities among multimorbid medical inpatients may increase awareness of what should be taken into account when treating such patients, a growth in the need for special care considerations.Cheating-a general term for extradyadic romantic or sexual behavior that violates expectations in a committed romantic relationship-is common and leads to a number of poor outcomes. Religion has historically influenced conceptions of romantic relationships, but societal attitudes about religion are in flux as many seek to retain spirituality even as affiliations with formal religion decrease. The present study evaluated a potential predictor of cheating that is more spiritual than formally religious, the "psychospiritual" concept of relationship sanctification (i.e., the idea that one's relationship itself is sacred). In a sample of college students in committed relationships (N = 716), we found that higher levels of self-reported relationship sanctification were associated with a lower likelihood of both physical and emotional cheating even when accounting for plausible alternate explanations (general religiosity, problematic alcohol use, and trait self-control). This association was mediated via permissive sexual attitudes; specifically, higher levels of sanctification were associated with less permissive sexual attitudes which, in turn, predicted a lower likelihood of emotional and physical cheating.Entertainment media consumed by adolescents have been criticized for their stereotyped depictions of sexual relationships. This longitudinal study among 182 boys and 218 girls from Belgium tests reciprocal relationships between adolescents' acceptance of gendered sexual roles and their exposure to music television and online pornography over three waves. see more The study innovates by including a fourth wave, approximately 5 years after Wave 3, when the participants had reached emerging adulthood, allowing to study long-term associations across the two developmental stages. Results first showed that adolescents who watched more music television than their same-aged peers reported a stronger acceptance of rape myths in emerging adulthood. Second, the link between adolescents' music television viewing and acceptance of rape myths in emerging adulthood was an indirect relationship through adolescents' acceptance of gendered sexual roles during adolescence. Third, adolescents' exposure to online pornography relative to their same-aged peers did not predict their acceptance of gendered sexual roles or rape myths in emerging adulthood. Fourth, gender and age differences could not be investigated due to model fit problems and are suggested to be examined in future research. Implications of the long-term consequences of adolescents' media use are discussed.PURPOSE To assess the dynamic of various health-related quality of life (HRQoL) parameters 3 years after pulmonary thromboendarterectomy (PTE), and to identify factors affecting HRQoL parameters in patients with chronic thromboembolic pulmonary hypertension (CTEPH) in the long-term follow-up after surgery. METHODS This prospective cohort study included 128 patients with CTEPH before and after the PTE (3 year follow-up). The HRQoL was examined using the Short-Form 36 Health Survey Questionnaire (SF-36). RESULTS In patients with CTEPH 3 years after PTE, a significant improvement in all the HRQoL parameters. The summary indicators of the physical and mental components of health remained at the same level as 1 year after the PTE and did not exceed 50 points. The residual pulmonary hypertension was a leading factor limiting parameters of physical and mental health 3 years after a PTE. In addition, the parameters of physical activity were adversely affected by age and the age-adjusted Charlson Comorbidity Index. CONCLUSIONS In the study group of patients with CTEPH, PTE contributes to a significant improvement in all HRQoL parameters, which observed both 1 year and 3 years after surgery. The leading factor adversely affecting the physical and emotional components of health in the long-term period after PTE was residual pulmonary hypertension recorded in the early postoperative period. In addition, some physical HRQoL parameters are affected by age and age-adjusted Charlson Comorbidity Index.The problem of developing research and innovation in accordance with society's general needs and values has received increasing attention in research policy. In the last 7 years, the concept of "Responsible Research and Innovation" (RRI) has gained prominence in this regard, along with the resulting question of how best to integrate awareness about science-society relations into daily practices in research and higher education. In this context, post-graduate training has been seen as a promising entrance point, but tool-kit approaches more frequently have been used. In this paper, we present and analyze an experiment-in the format of a Ph.D. course for early-career researchers-deploying an alternative approach. Drawing on Argyris and Schön's (1974) framing of reflective practice, and their distinctions between espoused theories and theories-in-use, the analyzed course endeavored to stimulate double-loop learning. Focusing on dislocatory moments, this paper analyses how the course tried to teach participants to reflect upon their own practices, values, and ontologies, and whether this provided them with the resources necessary to reflect on their theories-in-use in their daily practices.Cancers are a great threat to humans. In cancer therapy, surgical removal of the tumor combined with radiotherapy and chemotherapy is the most routine treatment procedure and usually the most effective. However, radiotherapy and chemotherapy drugs that kill cancer cells efficiently also kill normal cells, thus exhibiting large side effects. Cancer-targeted drugs, which aim to specifically recognize proteins or signaling pathways associated with tumor proliferation and migration, have achieved marked progress in recent years. Azurin is a copper-containing redox protein secreted by Pseudomonas aeruginosa. Azurin and its derived peptide p28 preferentially enter a variety of cancer cells and induce apoptosis or cell cycle arrest. Mechanistic studies revealed that azurin and p28 target the p53 and receptor tyrosine kinase signaling pathways as well as other pathways. Two phase I trials of p28 have been carried out, with findings that p28 is safe and exhibits anticancer activity in both adult and pediatric patients.