Mepolizumab focuses on multiple defense cells within aspirinexacerbated breathing condition

049). Furthermore, we found a significant decrease in the number of postoperative percutaneous nephrostomies and re-operations (7% versus none, P = 0.014). There was also a trend towards a decrease in other urinary complications such as postoperative bladder atony and uretero-vaginal fistulas. CONCLUSION The mesureter constitutes a convenient dissection plane enabling the preservation of lateral ureteral blood supply during TMMR. In our study, maintenance of mesureteral integrity was associated with a significant reduction in ureteral complications. Mesureteral preservation might also be useful in other types of pelvic surgeries that carry a high risk of ureteral damage. TWEETABLE ABSTRACT Surgical preservation of the mesureter in cervical cancer patients was associated with a reduction in urinary complications. © 2020 The Authors. BJOG An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd on behalf of Royal College of Obstetricians and Gynaecologists.WHAT IS KNOWN ON THE SUBJECT? Family-focused interventions in Adult Mental Health Services (AMHS) address the needs of families where a parent is diagnosed with a mental illness. One of these interventions is the "Let's Talk about Children" programme (Let's Talk) (Solantaus & Toikka, 2006 International Journal of Mental Health Promotion, 8(3), 37). There is limited implementation knowledge on family-focused interventions. A body of research to better understand the transfer of evidence-based interventions into everyday practice has identified multiple influencing elements. The Consolidated Framework for Implementation Research (CFIR) has combined these known elements from research into five domains of influence. Elements that influence the implementation of evidence-based practice are inter-related and need to be understood in combination. Understanding different stakeholder perspectives on implementation in real-world settings helps to understand uptake, challenges and opportunities. WHAT THE PAPER ADDS TO Eementation within an environment of constant change, and more attention is needed to understand the dynamics of parent and practitioner readiness for delivering Let's Talk. Implications for practice Different leadership roles need to be engaged to sustain Let's Talk in changing real-world environments. The dynamic processes between parent and practitioner are suggested to influence readiness and need further research. © 2020 John Wiley & Sons Ltd.INTRODUCTION Relatives are profoundly affected by an adult family member's severe and enduring mental health problem (MHP). The burdens of caring impact on adult relatives' emotional, physical and social wellbeing. How relatives make meaning and communicate about the MHP is thought to affect family talk about mental health and this can impact family coping and wellbeing. AIM No review has yet drawn together research about how adult relatives of people with severe and enduring MHP make meaning and communicate about their relatives' difficulties. We aimed to address this gap. METHOD We conducted a systematic review of peer-reviewed primary research. SCOPUS, Pubmed, Psychnet, SCIE, Cochrane and CINAHL+ databases were searched. RESULTS Nineteen papers qualified for inclusion. Findings are organised under four themes making meaning about the MHP and affected individual; conceptualising the self in the presence of the MHP; meaning making processes underlying relatives' wellbeing outcomes; and relatives' perspectives on family talk about the MHP. DISCUSSION Historical relationships, caregiver identity and mental health literacy moderate relatives' understanding and talk about the MHP. IMPLICATIONS FOR PRACTICE Psychoeducation and communication support for relatives should be provided by mental health practitioners. Future research should address familial communication about MHP , including with children. This article is protected by copyright. All rights reserved.In fascinating recent work, some philosophers have argued that it would be morally permissible and prudentially rational to sign up for cryonics-if you can afford the price tag of the procedure. In this paper I ask why not share the elixir of extended life with everyone? Should governments financially support, positively encourage, or even require people to undergo cryonics? From a general principle of beneficence, I construct a formal argument for cryonics promotion policies. I consider the objection that a subset of these policies would violate autonomy, but I argue that-to the contrary-considerations of autonomy weigh in their favour. I then consider objections based on cost and population, but argue that neither is fatal. Finally, I raise the objection that I believe poses the most serious challenge that those who revive the cryonically preserved might inflict suffering upon them. © 2020 John Wiley & Sons Ltd.Between 1910 and 1947, Robert Robinson (primarily) among others published numerous proposed structures for strychnine.  Robinson published 17 of his strychnine papers with his doctoral advisor William Henry Perkin, Jr., though all but 2 appeared after Robinson had taken his first permanent academic position.  This paper reports on and analyzes 20 key publications leading up to Robinson's (correct, then incorrect, then correct again though not definitive) proposal and Woodward's assignment of the actual structure of strychnine.  We subjected the assignment of the strychnine structure to a modern computational quantum chemistry workflow. Selleck MEK inhibitor  By computing, with density functional theory, 1H and 13C chemical shifts for the literature-proposed strychnine structures, we were able to rule out most incorrect structures. 13C NMR predictions were better at this, but 1H chemical shifts were helpful.  A comparison is made between the consequences of publishing erroneous ideas in the first half of the 20th century and doing so in the 21st century. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.AIM To explore the visibility of nursing in policy documents concerning healthcare priorities in the Nordic countries. BACKGROUND Nurses at all levels in healthcare organizations set priorities on a daily basis. Such prioritization entails allocation of scarce public resources with implications for patients, nurses, and society. Although prioritizations in healthcare has been on the political agenda for many years, prioritization in nursing seems to be obscure in policy documents. METHODOLOGY Each author searched for relevant documents from their own country. Text analyses were conducted of the included documents concerning nursing visibility. RESULTS All the Nordic countries have published documents articulating values and criteria relating to healthcare priorities. Nursing is seldom explicitly mentioned but rather is included and implicit in discussions of healthcare prioritization in general. CONCLUSION There is a need to make priorities in nursing visible to prevent missed nursing care and ensure fair allocation of limited resources.